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Identify steps in glycolysis that illustrate the use of coupled reactions to drive thermodynamically unfavored processes, including substrate-level phosphorylation

Panel B of Figure 5 shows that the fluctuations in methionine input cause very large fluctuations in SAM but only modest fluctuations in intracellular methionine concentration, as suggested by the early methionine loading experiments of Finkelstein and co-workers [53, 54]

[2] Crystalloids generally are much cheaper than colloids

Magnesium supplementation has shown benefit in some individuals with ASD, particularly those with hyperexcitability, sensory sensitivity, and sleep disturbances